To support dairy manufacturers as they respond to recent food safety concerns, we've introduced a new test for the detection of cereulide in infant formula, other dairy products and raw materials.
In line with international best practice, cereulide is quantitatively determined by LC-MS/MS analysis following ISO 18465:2017, ensuring robust detection, accurate quantification and reliable risk assessment.
The new method offers a limit of reporting of 0.01 µg/kg (0.01 ppb). This level is below the European Food Safety Authority acute reference dose (ARfD) for cereulide in infants, which is 0.014 µg/kg body weight. This ARfD corresponds to an estimated concentration of 0.054 µg/kg cereulide in reconstituted infant formula.
Analysis Test Codes – New Tests / Methods
| Test Code | Variation Description | Description (Reportable Components) | Method Reference | LOR (µg/kg) | Accreditation* | Matrix** | TAT |
| MN-CERE01 v01 | Quantitative Results | Cereulide | ISO 18465: 2017 | 0.030 | 2.70 | Dairy Powders, Raw Materials | 10 Days |
| MN-CERE01 v02 | Qualitative Results | Cereulide | ISO 18465: 2017 | Not Detected | 2.70 | Dairy Powders, Raw Materials | 10 Days |
| MN-CERE01 v03 | Quantitative Results | Cereulide | ISO 18465: 2017 | 0.010 | 2.70 | Dairy Liquids, Reconstituted Powders | 10 Days |
| MN-CERE01 v04 | Qualitative Results | Cereulide | ISO 18465: 2017 | Not Detected | 2.70 | Dairy Liquids, Reconstituted Powders | 10 Days |
* The results are currently covered under ISO/IEC 17025 accreditation through the IANZ 2.70 Special Class within our scope; however, we are actively pursuing IANZ scope update.
**Milk powders, infant formulas, adult/paediatric nutritional formulas, milk, reconstituted milk, other dairy products and raw materials like ARA / DHA powders.
For full information about the new test method, please see Quantitative Determination of Emetic Toxin (Cereulide) Using LC-MS/MS (ISO 18465: 2017) (customer sign-in required).
Next steps
If your organisation would like to being using this test our team is ready to support you.
See here for further information on creating or updating your product specifications to include this testing and update your LabConnect templates as required to incorporate the test.
Please submit a request if you would like more information or a quote for this testing.
Please update any internal documentation such as quality manuals and specifications.